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On a body surface area basis, this dose in the mouse and rat is, respectively, about equal to and about twice the maximum recommended human oral daily dose (MRHD) of 640 mg propranolol hydrochloride.

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Propranolol for Infantile Hemangiomas: A Review".

Dosage adjustment does not seem necessary in either patient population based on pharmacokinetic findings.

Since coronary artery disease may be unrecognized, it may be prudent to follow the above advice in patients considered at risk of having occult atherosclerotic heart disease who are given propranolol for other indications.

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Do not drink alcohol while using the medication; it can increase the levels of Inderal (Propranolol) in your blood.

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Beta-blockers affect beta-receptors and help block the peripheral effects of norepinephrine, epinephrine (adrenaline), and other stress hormones, thus affecting the fight-or-flight response.

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Propranolol is also a substrate of CYP2C19 and a substrate for the intestinal efflux transporter, p-glycoprotein (p-gp).

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Recent evidence (June 2008) suggests that propranolol can be used to treat severe infantile hemangiomas (IHs).

Ask your health care provider any questions you may have about how to use Inderal.

Do not swallow the tablet whole, do not chew it, use it as soon as you open the blister.

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